Head to Toe
Thyroid Health
- Thyroid Problems
- Fatigued or Full Throttle: Is Your Thyroid to Blame?
- What's Causing My Low Thyroid Level?
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- Symptoms of Hypothyroidism
- Hypothyroidism and Depression
- How Hypothyroidism Is Treated
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- Thyroid Problems
Understanding Thyroid Problems -- the Basics
Through the hormones it produces, the thyroid gland influences almost all of the metabolic processes in your body. Thyroid disorders can range from a small, harmless goiter (enlarged gland) that needs no treatment to life-threatening cancer. The most common thyroid problems involve abnormal production of thyroid hormones. Too much thyroid hormone results in a condition known as hyperthyroidism. Insufficient hormone production leads to hypothyroidism.
Although the effects can be unpleasant or uncomfortable, most thyroid problems can be managed well if properly diagnosed and treated.
What Causes Thyroid Problems?
All types of hyperthyroidism are due to an overproduction of thyroid hormones, but the condition can occur in several ways:
- Graves' disease: The production of too much thyroid hormone.
- Toxic adenomas: Nodules develop in the thyroid gland and begin to secrete thyroid hormones, upsetting the body's chemical balance; some goiters may contain several of these nodules.
- Subacute thyroiditis: Inflammation of the thyroid that causes the gland to "leak" excess hormones, resulting in temporary hyperthyroidism that generally lasts a few weeks but may persist for months.
- Pituitary gland malfunctions or cancerous growths in the thyroid gland: Although rare, hyperthyroidism can also develop from these causes.
Hypothyroidism , by contrast, stems from an underproduction of thyroid hormones. Since your body's energy production requires certain amounts of thyroid hormones, a drop in hormone production leads to lower energy levels. Causes of hypothyroidism include:
- Hashimoto's thyroiditis : In this autoimmune disorder, the body attacks thyroid tissue. The tissue eventually dies and stops producing hormones.
- Removal of the thyroid gland: The thyroid may have been surgically removed or chemically destroyed.
- Exposure to excessive amounts of iodide: Cold and sinus medicines, the heart medicine amiodarone, or certain contrast dyes given before some X-rays may expose you to too much iodine.You may be at greater risk for developing hypothyroidism if you have had thyroid problems in the past.
- Lithium : This drug has also been implicated as a cause of hypothyroidism.
Untreated for long periods of time, hypothyroidism can bring on a myxedema coma, a rare but potentially fatal condition that requires immediate hormone treatment.
Hypothyroidism poses a special danger to newborns and infants. A lack of thyroid hormones in the system at an early age can lead to the development of cretinism (mental retardation) and dwarfism (stunted growth). Most infants now have their thyroid levels checked routinely soon after birth. If they are hypothyroid, treatment begins immediately. In infants, as in adults, hypothyroidism can be due to these causes:
- A pituitary disorder
- A defective thyroid
- Lack of the gland entirely
A hypothyroid infant is unusually inactive and quiet, has a poor appetite, and sleeps for excessively long periods of time.
Cancer of the thyroid gland is quite rare and occurs in about 5% of thyroid nodules. You might have one or more thyroid nodules for several years before they are determined to be cancerous. People who have received radiation treatment to the head and neck earlier in life, possibly as a remedy for acne, tend to have a higher-than-normal risk of developing thyroid cancer.
- Fatigued or Full Throttle: Is Your Thyroid to Blame?
Fatigued or Full Throttle: Is Your Thyroid to Blame?
Feeling all revved up, even at bedtime? Or maybe your throttle's on idle with symptoms of depression, fatigue, and weight gain. In both cases, the root cause may be your thyroid.
The thyroid -- a butterfly-shaped gland in the front of your neck -- makes hormones that control the way your body uses energy. Your thyroid controls your metabolism, which is how your body turns food into energy, and also affects your heart, muscles, bones, and cholesterol.
While thyroid disorders can range from a small, harmless goiter (enlarged gland) to life-threatening cancer, the most common thyroid problemsinvolve an abnormal production of thyroid hormones. If there is too much of these vital body chemicals, the result is a condition known as hyperthyroidism. Too little hormone production leads to hypothyroidism.
Although the effects of thyroid problems are unpleasant or uncomfortable, most thyroid conditions can be managed well if properly diagnosed and treated.
What Is an Overactive Thyroid?
Hyperthyroidism happens when the thyroid becomes overactive and produces too much of its hormones. Hyperthyroidism affects women five times to 10 times more often than men, and is most common in people younger than 40. People with hyperthyroidism have problems that reflect over activity of the body's organs, resulting in such symptoms as sweating, feeling hot, rapid heartbeat, weight loss, and sometimes eye problems.
Hyperthyroidism can occur in several ways:
Graves' disease: The release of excess hormones is triggered by an autoimmune disorder. For some unknown reason, the body attacks the thyroid, causing it to spill out too much hormone.
Toxic adenomas: Nodules (abnormal growths or lumps) develop in the thyroid gland and begin to secrete thyroid hormones, upsetting the body's chemical balance. Some goiters may contain several of these nodules.
Subacute thyroiditis: Painful inflammation of the thyroid causes the gland to enlarge and "leak" excess hormones, resulting in temporary hyperthyroidism, which resolves spontaneously. Subacute thyroiditis generally lasts a few weeks but may persist for months.
Pituitary gland malfunctions or cancerous growths in the thyroid gland: Although rare, hyperthyroidism can also develop from these causes.
Silent thyroiditis: This is usually a temporary state of excess thyroid hormone release causing mild hyperthyroidism. In some cases it can result in permanent damage to the thyroid and low thyroid hormone production by the gland.
Postpartum thyroiditis: This is a type of hyperthyroidism that occurs in a small percentage of women within months of delivery. It last only a few months, followed by several months of reduced amounts of thyroid hormone production by the gland. Typically these women fully recover normal thyroid function.
Ingestion of excess thyroid hormone can result in hyperthyroidism.
What Is an Underactive Thyroid?
Hypothyroidism, by contrast, stems from an underproduction of thyroid hormones. Since your body's energy production requires certain amounts of thyroid hormones, a drop in hormone production leads to lower energy levels, causing you to feel weak and tired.
Approximately 25 million people suffer with hypothyroidism and about half are undiagnosed. Older adults -- particularly women -- are more likely to develop hypothyroidism than younger adults. Hypothyroidism also tends to run in families.
If hypothyroidism is not treated, it can raise your cholesterol levels and make you more likely to have a heart attack or stroke. During pregnancy, untreated hypothyroidism can harm your baby. Luckily, hypothyroidism is easy to treat.
Causes of hypothyroidism may include:
Hashimoto's thyroiditis: In this autoimmune disorder, the body attacks thyroid tissue. The tissue eventually dies and stops producing hormones. Other autoimmune disorders occur with this condition and other family members may also be affected by this condition.
Removal of the thyroid gland: The thyroid may be surgically removed or chemically destroyed as treatment for hyperthyroidism.
Exposure to excessive amounts of iodide: The heart medicine amiodaronemay expose you to too much iodine. Radioactive iodine treatment for hyperthyroidism can also result in hypothyroidism. You may be at greater risk for developing hypothyroidism, especially if you have had thyroid problems in the past.
Lithium: This drug has also been linked as a cause of hypothyroidism.
If left untreated for a long period of time, hypothyroidism can bring on a myxedema coma, a rare but potentially fatal condition that requires immediate hormone injections.
How Is Hypothyroidism or Hyperthyroidism Diagnosed?
Your doctor will ask you about your symptoms and do a physical exam. Then he or she will order blood tests to see how much thyroid hormone your body is making. In addition, your doctor may discover that you have hyperthyroidism while doing a test for another reason.
Signs and Symptoms of a Thyroid Problem:
- You may feel nervous, moody, weak, or tired.
- Your hands may shake, your heart may beat fast, or you may have problems breathing.
- You may be sweaty or have warm, red, itchy skin.
- You may have more bowel movements than usual.
- You may have fine, soft hair that is falling out.
- You may feel tired, weak, and/or depressed.
- You may have dry skin and brittle nails.
- You may have difficulty standing cold temperatures.
- You may have constipation.
- You may experience memory problems or trouble thinking clearly.
- You may have heavy or irregular menstrual periods.
- You may lose weight even though you eat the same or more than usual.
Symptoms of hypothyroidism occur slowly over time. At first you might not notice these symptoms. Or you might mistake them for normal aging. This is not normal aging. See your doctor if you have symptoms like these that get worse or won't go away.
Pregnancy, which requires an increased production of thyroid hormone, can cause hypothyroidism. About 2% of pregnant women in the United States get hypothyroidism.
How Is Hyperthyroidism Treated?
Hyperthyroidism is easily treated. With treatment, you can lead a healthy life. Without treatment, hyperthyroidism can lead to serious heart problems, bone problems, and a dangerous condition called thyroid storm.
If your symptoms bother you, your doctor may give you pills called beta-blockers. These can help you feel better while you and your doctor decide what your treatment should be. Even if your symptoms do not bother you, you still need treatment because hyperthyroidism can lead to more serious problems.
Radioactive iodine and anti-thyroid medicine are the treatments doctors use most often. The best treatment for you will depend on a number of things, including your age. Some people need more than one kind of treatment.
After treatment, you will need regular blood tests. These tests check to see if your hyperthyroidism has come back. They also check to see if you are making enough thyroid hormone. Sometimes treatment cures hyperthyroidism but causes the opposite problem-too little thyroid hormone. If this happens, you may need to take thyroid hormone pills for the rest of your life.
What Medicine Is Used for Hypothyroidism?
Doctors usually prescribe thyroid hormone pills to treat hypothyroidism. Most people start to feel better within a week or two. Your symptoms will probably go away within a few months. But you will likely need to keep taking the pills for the rest of your life.
In most cases, thyroid hormone medication works quickly to correct symptoms. People with hypothyroidism who take thyroid hormone medication usually notice:
- Improved energy level
- Gradual weight loss (in people with severe hypothyroidism at the time of diagnosis)
- Improved mood and mental function (thinking, memory)
- Improved pumping action of the heart and improved digestive tract function
- Reduction in the size of an enlarged thyroid gland (goiter), if you have one
- Lower cholesterol and triglyceride levels
It's important to take your medicine just the way your doctor tells you to. You will also need to see your doctor for follow-up visits to make sure you have the right dose. Getting too much or too little thyroid hormone can cause problems.
If you have mild (subclinical) hypothyroidism, you may not need treatment now. But you'll want to watch closely for signs that it is getting worse.
Thyroid Disease or Menopause?
According to the American Association of Clinical Endocrinologists (AACE), millions of women with unresolved menopausal-like symptoms, even those taking estrogen, may be suffering from undiagnosed thyroid disease. While symptoms such as fatigue, depression, mood swings, and sleepdisturbances are frequently associated with menopause, they may also be signs of hypothyroidism.
A survey done by the AACE showed that only one in four women who have discussed menopause and its symptoms with a physician was also tested for thyroid disease. The thyroid plays a role in regulating overall body metabolism and influences the heart, brain, kidney, and reproductive system, along with muscle strength and appetite.
If you are experiencing symptoms of menopause and the symptoms persist despite appropriate therapy, ask your doctor to do a thyroid screen (TSH). A blood sample is all that is needed to make the initial diagnosis of hypothyroidism and treatment is easily achieved with thyroid replacement therapy.
What About Thyroid Cancer?
Cancer of the thyroid gland is quite rare and occurs in less than 10% of thyroid nodules. You might have one or more thyroid nodules for several years before they are determined to be cancerous. People who have received radiation treatment to the head and neck earlier in life, possibly as a remedy for acne, tend to have a higher-than-normal propensity for thyroid cancer.
Signs and Symptoms:
- You may get a lump or swelling in your neck. This is the most common symptom.
- You may have pain in your neck and sometimes in your ears.
- You may have trouble swallowing.
- You may have trouble breathing or have constant wheezing.
- Your voice may be hoarse.
- You may have a frequent cough that is not related to a cold.
Some people may not have any symptoms. Their doctors may find a lump or nodule in the neck during a routine physical exam.
Most people who have treatment for thyroid cancer do very well, because the cancer is usually found early and the treatments, including surgery, work well. Once treated, thyroid cancer rarely returns.
- What's Causing My Low Thyroid Level?
What's Causing My Low Thyroid Level?
Autoimmune diseases, surgery, and radiation treatment are possible reasons why your thyroid gland isn't making enough thyroid hormone to meet your body's needs. Whatever the cause, medicine can get your hypothyroidism under control.
Hashimoto's Thyroiditis
This is the most common reason for low thyroid levels in the U.S. It's an autoimmune disease, meaning your immune system mistakenly attacks your body's healthy cells. In this case, it destroys the cells that make thyroid hormone.
Surgery on the Thyroid Gland
You can get hypothyroidism if you've had surgery to remove part or all of your thyroid gland. It's sometimes done if you have a growth on your thyroid or if it's making too much hormone.
Getting the entire gland removed always leads to hypothyroidism. For some people, if only part of it is taken out, the part that's left may still be able to make enough thyroid hormone.
Treatment With Radiation
Radiation can damage the cells that make thyroid hormone. You might get treated with radiation for:
- Overactive thyroid gland
- Cancer of the head or neck
- Hodgkin's disease or lymphoma (cancer of the lymph system)
Thyroid Swelling
A bacterial or viral infection can make your thyroid gland swell. This is called thyroiditis. The damaged thyroid leaks its hormone into your blood, which causes your thyroid hormone level to rise for a short time. Once that hormone is used up, your thyroid hormone levels will drop.
Low levels from thyroiditis often don't last long, because the gland hasn't been permanently damaged.
Women can get thyroiditis after they give birth, called postpartum thyroiditis. It's thought to be an autoimmune disease, much like Hashimoto's thyroiditis.
Medicines
Some medicines can affect how your thyroid works and lead to low hormone levels. These include:
- Lithium, used for bipolar disorder and depression
- Interferon alpha, which treats cancer
- Amiodarone (Cordarone, Pacerone), a treatment for heart rhythm problems
- Interleukin-2, used for kidney cancer
Too Little or Too Much Iodine
Your thyroid gland needs iodine to make its hormone. You get it from many of the foods you eat. Not getting enough is rare in the U.S. because it's added to many foods. The problem is more common in developing countries.
You can also have a low thyroid level if you get too much iodine. It blocks the gland from making its hormone. It can also lead to an overactive thyroid.
Hypothyroidism at Birth
Sometimes, babies are born with a missing or poorly formed thyroid gland. This is called congenital hypothyroidism.
Damage to the Pituitary Gland
Less often, low thyroid level is caused by a problem outside the gland. The culprit may be the pituitary gland at the base of the brain, which directs your thyroid to make its hormone. If the pituitary is damaged from a tumor, surgery, or radiation, it may not be able to give instructions to the thyroid.
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